Differential Pulse Voltammetric Determination of Clozapine in Drug Dosage Forms at Bismuth Film Electrode

نویسندگان

چکیده

A new differential pulse voltammetric method for the determination of clozapine in drug dosage forms has been described. In this study, amount commercial determined at bismuth modified glassy carbon electrode by taking advantage electrochemical oxidation it. The was with BiCl3 to prepare film electrode. acetate buffer solution pH = 5.00 selected as supporting electrolyte where maximum current observed effect on peak and potential investigated voltammetry (DPV), scan rate examined cyclic (CV). With developed method, detection limit working range 1×10-6 M 10×10-6 found be 6.112×10-9. tablets stated after analytical parameters. recovery study executed check accuracy precision applied method.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Differential pulse adsorptive stripping voltammetric determination of dinoseb and dinoterb at a modified electrode.

A sensitive adsorptive stripping voltammetric method for the determination of dinitrophenolic herbicides, dinoseb (DSB) and dinoterb (DTB) at a bare carbon paste electrode (CPE) and a clay modified carbon paste electrode (CMCPE) was developed. A systematic study of various experimental conditions, such as the pH, accumulation variables and composition of a modifier on the adsorptive stripping r...

متن کامل

Adsorptive voltammetric determination of chlordiazepoxide in pure and dosage forms

The behavior of chlordiazepoxide has been studied using dc-polarography at dropping mercury electrode (DME) and cyclic voltammetry at glassy carbon electrode (GCE). In Britton-Robinson buffers, the drug developed three reduction irreversible waves in acidic solutions, and only two waves in alkaline media. The adsorptive stripping voltammetric behavior of chlorodiazepoxide was studied at GCE, an...

متن کامل

Differential pulse anodic stripping voltammetric determination of traces of copper with a tobramycin-Nafion modified electrode.

A Nafion-modified glassy carbon electrode incorporated with tobramycin for the voltammetric stripping determination of Cu2+ has been explored. The electrode was fabricated by tobramycin containing Nafion on the glassy carbon electrode surface. The modified electrode exhibited a significantly increased sensitivity and selectivity for Cu2+ compared with a bare glassy carbon electrode and the Nafi...

متن کامل

Selective Determination of Trace-Bismuth by Extraction-Differential Pulse Polarography in Non-Aqueous Media

The voltammetric characteristics of bismuth(III)-oxinate in chloroform at the mercury electrode were investigated and a quasi-reversible behavior for Bi(III) oxinate reduction was confirmed. Preceded by the extraction of Bi(III) oxinate in chloroform, differential pulse polarography was developed in the extracts for determination of the trace-bismuth. The linear range of the calibration gra...

متن کامل

Differential pulse adsorption stripping voltammetric determination of copper(II) with 2-mercaptobenzimidazol at a hanging mercury-drop electrode.

Copper(II) was selectively accumulated on a hanging mercury-drop electrode by using 2-mercaptobenzimidazole. Ensuing measurements were carried out by differential pulse adsorption stripping voltammetry. Factors affecting the accumulation, reduction, and stripping steps were investigated and a procedure was developed. The optimum conditions for the analysis of copper were pH 5.0, 5.33 x 10(-5) M...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Hitite journal of science and engineering

سال: 2021

ISSN: ['2148-4171', '2149-2123']

DOI: https://doi.org/10.17350/hjse19030000215